Cell stem cellAnimalsMiceEmbryoMammalianEmbryonic Stem Cells
Building the start: Unlocking advanced stem cell-based embryo models.
Zekun Wu, Hongan Ren, Leqian Yu
Published: 202510.1016/j.stem.2025.08.016
Abstract
Two recent studies from the Silva and Hanna groups optimized chemical induction and culture conditions to derive extraembryonic lineages directly from embryonic stem cells (ESCs) without transgenes, enabling mouse stem cell-based embryo models (SCBEM…
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