Seminars in cancer biologyHumansNeoplasmsEpigenesisGeneticGlycolysis
Protein lactylation in cancer and other pathologies: Epigenetic regulation of glycolysis and its therapeutic perspectives.
Yaowen Zhang, Jianxiang Wang, Cong Li, Zhe Lei, Xiang Zhao, Xuan Xuan, Olga Sukocheva, Edmund Tse, Junqi Liu
Published: 202610.1016/j.semcancer.2025.12.005
Abstract
Lactylation, a recently recognized post-translational protein modification, is reshaping research in epigenetics and molecular medicine. Emerging evidence indicates that lactylation plays a critical role in the onset and progression of cancer, as wel…
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