The Science of the total environmentPsoriasisHumansDiethylhexyl PhthalatePlasticizersEnvironmental Exposure
DEHP promotes psoriasis via immune modulation and direct molecular interactions: Evidence from epidemiology, multi-omics, and structural simulation.
Xulei Zuo, Xiaoyu Hou, Yuxi Zhang, Cong Zhang, Juan Zhang
Published: 202510.1016/j.scitotenv.2025.180723
Abstract
Di (2-ethylhexyl) phthalate (DEHP), a widely used plasticizer with known immunotoxic effects, has been suspected of aggravating inflammatory skin conditions, yet its role in autoimmune diseases such as psoriasis remains poorly defined. In this study,…
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