Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Real-time concentration prediction in column chromatography purification using NIR optical sensing and evolutionary attention-LSTM modeling.
Dandan Zhai, Jinfeng Liu, Jingyun Liu, Mingxing Li, Anqi Liu, Yu Yang, Zhenwei Zhang, Na Liu, Ming Hui, Peng Li
Published: 202610.1016/j.saa.2026.127463
Abstract
Ginsenosides, the principal bioactive constituents of American ginseng (Panax quinquefolius), require precise monitoring during column chromatography to ensure product quality. Conventional assays are time-consuming and unsuited for real-time process…
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