Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Imaging alkaline phosphatase activity in alcoholic liver disease via a rational-designed NIR fluorogenic probe.
Guilin Ding, Xiaoteng Ma, Lingli Wang, Qingqi Tuo, Jiamin Wang, Jinying Liu, Jian Zhang
Published: 202610.1016/j.saa.2026.127459
Abstract
Alkaline phosphatase is a zinc-based metalloenzyme present in various tissues, and its levels increase in alcoholic liver injury. Herein, we report an enzyme-activatable NIR probe, BDP-R-ALP, that enables highly sensitive and selective detection of a…
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