Spectrochimica acta. Part A, Molecular and biomolecular spectroscopyAnimalsFluorescent DyesChemical and Drug Induced Liver InjuryViscosityMice
A novel mitochondria-targeted red-light emission fluorescent probe for monitoring the viscosity in drug-induced liver injury.
Yeming Zhang, Jing Yang, Yuqing Wang, Kun Yu, Fan Wang, Yunjia Zhao, Lei Hu, Hui Wang
Published: 202610.1016/j.saa.2025.127062
Abstract
Drug-induced liver injury (DILI) remains a major challenge in clinical drug development and application. Hepatocyte dysfunction is central to its pathogenesis, with intracellular viscosity serving as an early biophysical marker of cellular state. Her…
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