Respiratory medicine
Anti-MDA5 antibody-positive interstitial lung disease without prominent skin or muscle manifestations: A high-risk and potentially overlooked subgroup.
Atsushi Muto, Satoshi Watanabe, Yuko Waseda, Seisuke Okazawa, Toshiki Kido, Keigo Saeki, Toshiyuki Kita, Hazuki Takato, Hiroki Shirasaki, Yukio Kawagishi, Kenta Yamamura, Kazumasa Kase, Kazuhiko Iwasaki, Satoshi Tanaka, Yasunori Iwata
Published: 202510.1016/j.rmed.2025.108629
Abstract
PURPOSE: Anti-melanoma differentiation-associated gene 5 (MDA5) antibody is associated with clinically amyopathic dermatomyositis (CADM) and life-threatening rapidly progressive interstitial lung disease (RP-ILD). Although ILD without skin or muscle…
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