Respiratory medicineHumansAsthmaReceptorsGlucocorticoidMale
Variants in the Glucocorticoid Receptor gene (NR3C1), asthma control and serum cytokine levels.
Maria Borges Rabêlo de Santana, Álvaro A Cruz, João Locke Ferreira de Araújo, Rafaela Machado Tugores, Helena Mariana Pitangueira Teixeira, Talita Santos de Jesus, Gabriela Pimentel, Cinthia Vila Nova Santana, Nazanin Zounemat Kermani, Kian Fan Chung, Ian M Adcock, Adelmir Souza-Machado, Camila Alexandrina Figueiredo, Ryan Dos Santos Costa
Published: 202610.1016/j.rmed.2025.108553
Abstract
INTRODUCTION: Asthma is a heterogeneous disease usually treated with inhaled corticosteroids (ICS) and long-acting beta2 agonists. However, not all individuals achieve adequate control with ICS. AIM: To identify genetic variants in the glucocorticoid…
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