Respiratory medicineHumansFemaleMaleMiddle AgedFamilial Primary Pulmonary Hypertension
Polygenic risk score and clinical factors predict incident idiopathic pulmonary arterial hypertension.
Song Hu, Jiang-Shan Tan, Shengsong Zhu, Lu Hua, Zhennan Lin, Jian Zhang
Published: 202510.1016/j.rmed.2025.108404
Abstract
BACKGROUND: This study aimed to develop a comprehensive prediction model integrating polygenic risk scores (PRS) and clinical factors to identify individuals at high risk for incident idiopathic pulmonary arterial hypertension (IPAH). METHODS: A PRS…
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