ResuscitationInterleukin-17AnimalsMaleRatsHumans
IL-17A monoclonal antibody as a translational therapy for post-cardiac arrest brain injury: clinical and preclinical evidence.
Qiyu Zhao, Tian Pei, Chen Sun, Hongning Yang, Wei Zhuang, Shuqun Hu, Tie Xu, Xianliang Yan, Chenglei Su
Published: 202610.1016/j.resuscitation.2025.110876
Abstract
BACKGROUND: Post-cardiac arrest brain injury (PCABI) is a major cause of mortality and disability among cardiac arrest (CA) survivors. The role of interleukin-17A (IL-17A) as a prognostic biomarker and therapeutic target in PCABI remains unvalidated.…
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