Respiratory investigationHumansMucusMaleFemaleMiddle Aged
Differential associations between type 2 inflammation and airway mucus plugs in asthma, asthma-COPD overlap, and COPD.
Kazuki Oga, Yusuke Hayashi, Naoya Tanabe, Tomoki Maetani, Yusuke Shiraishi, Ryo Sakamoto, Hironobu Sunadome, Susumu Sato, Hisako Matsumoto, Atsuyasu Sato, Toyohiro Hirai
Published: 202510.1016/j.resinv.2025.10.007
Abstract
BACKGROUND: The mechanisms by which type 2 (T2) inflammation affects airway mucus plugging in asthma, asthma‒chronic obstructive pulmonary disease (COPD) overlap (ACO), and COPD remain unclear despite their clinical relevance. This study examined whe…
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