Respiratory investigationHumansAntigensBacterialLegionnaires' DiseaseSensitivity and Specificity
The LIAISON® Legionella Urinary Ag assay: A novel high-throughput, fully automated dual-antigen detection method with improved sensitivity and expanded Legionella species and serogroup coverage.
Serena Ferraiuolo, Farah Bou Nasser Eddine, Deborah Ferrante, Andrea Dal Corso, Lorenzo Querin, Marco Rigamonti, PierNatale Brusasca, Alfredo Mento, Antonio Savinelli, Karolina Zytko, Massimo Panizzo, Elisa Ghezzi, Clara Rossini, Chiara Mauro, Andrea Pighini
Published: 202510.1016/j.resinv.2025.09.006
Abstract
BACKGROUND: Legionella pneumophila is a leading cause of Legionnaires' disease, with Legionella pneumophila serogroup 1 (Lp1) being the most commonly detected strain. Current urinary antigen tests (UAT) primarily target Lp1, leading to underdiagnosis…
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