Metabolic reprogramming and organelle quality control: The "silent" drivers of Sertoli cell dysfunction under environmental stressors.

Sertoli cells (SCs) are the metabolic and structural "nurse" cells of the seminiferous epithelium. Classical testicular toxicology has largely focused on endpoints such as germ cell apoptosis, testicular atrophy and overt Sertoli cell death. These ou…

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