Reproductive toxicology (Elmsford, N.Y.)
Total Flavonoids of Epimedium Ameliorate Testicular Damage via Keap1-Nrf2/ARE Signalling and Multi-Target Regulation.
Hongchao Yuan, Wenhao Tian, Hao Hao, Sirui Kang, Fanfan Jia, Kai Chen, Xiaoying Zhang, Chen Chen
Published: 202510.1016/j.reprotox.2025.109142
Abstract
This study investigates the protective effects of total flavonoids of Epimedium (TFE) against obesity-induced testicular damage in mice. The potential pharmacological mechanisms were predicted using network pharmacology, molecular docking and molecul…
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