Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
A seven-gene 5-hydroxymethylcytosine signature in circulating cell-free DNA for prognostic stratification of nasopharyngeal carcinoma.
Bijuan Chen, Di Wang, Jiali Huang, Sisi Yu, Siping Fang, Chuying Chen, Jie Wang, Jianji Pan, Shaojun Lin, Qiaojuan Guo, Yun Xu, Zhouwei Zhan
Published: 202610.1016/j.radonc.2026.111366
Abstract
BACKGROUND: Circulating cell-free DNA (cfDNA) 5-hydroxymethylcytosine (5hmC) is a promising epigenetic biomarker in cancer. Its prognostic role in nasopharyngeal carcinoma (NPC), however, remains unclear. METHODS: Genome-wide 5hmC profiling was condu…
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