Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and OncologyAnimalsMiceDose FractionationRadiationInbred C57BL
Decrease in dose per fraction impairs the FLASH sparing effect in murine intestine model.
A Sesink, R Geyer, P Devanand, T T Böhlen, L Soutter, R Moeckli, C Bailat, F G Herrera, V Grilj
Published: 202610.1016/j.radonc.2025.111262
Abstract
PURPOSE: FLASH radiotherapy (FLASH) can ease radiation-induced normal tissue toxicities; however, its benefit in clinically relevant fractionation protocols remains insufficiently explored. This study investigated the FLASH sparing effect under two f…
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