Pulmonary pharmacology & therapeutics
Targeting ELK-1 transcription factor and mechanosensitive MDM4 receptor using an HCN channel blocker alleviates lung fibrosis.
Sahar A Helmy, Nesma A Abd Elrazik
Published: 202610.1016/j.pupt.2026.102408
Abstract
Idiopathic pulmonary fibrosis is a progressive interstitial lung disease associated with poor prognosis and high mortality rate. It is a chronic irreversible lung disorder, mainly characterized by matrix stiffening. This study aims to investigate the…
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