Pathology, research and practiceHumansUbiquitin-Protein LigasesChronic DiseaseSignal TransductionProtein Kinases
Therapeutic potential of natural compounds in the management of chronic diseases: Targeting PINK1-Parkin pathway.
Naglaa F Khedr, Hend M Selim, Gamal A Abourayya
Published: 202610.1016/j.prp.2025.156284
Abstract
Chronic diseases like neurodegenerative disorders, musculoskeletal issues, metabolic diseases, cancer, liver and kidney disorders are increasingly linked to mitochondrial dysfunction. PINK1-Parkin-mediated mitophagy, a vital autophagic process, plays…
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