Pathology, research and practiceHumansEnterotoxinsImmunotherapyNeoplasmsAnimals
Staphylococcal enterotoxins in cancer immunotherapy: An overview of translational advances and targeting strategies.
Abbas Ali Imani Fooladi, William C Cho, Russel J Reiter, Mina Alimohammadi, Najma Farahani, Kiavash Hushmandi
Published: 202510.1016/j.prp.2025.156283
Abstract
Staphylococcal enterotoxins (SEs) are superantigens that polyclonally activate T cells by cross-linking MHC class II on antigen-presenting cells with T cell receptor (TCR) Vβ regions, generating potent IL-2/IFN-γ/TNF responses distinct from conventio…
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