Progress in neuro-psychopharmacology & biological psychiatryAnimalsFemaleMicrogliaRatsValproic Acid
Uncovering the female phenotype in the VPA autism model: Brain-region specific synaptic pattern, microglial priming and behavioral singularity.
Marianela E Traetta, Martin G Codagnone, Einav Litvak, María José Maleville Corpa, Nonthué A Uccelli, Sandra C Zárate, Analía G Reinés
Published: 202610.1016/j.pnpbp.2025.111591
Abstract
Neurodevelopmental disorders, such as autism spectrum disorders (ASD), exhibit a poorly understood male bias. While sex differences may provide key insights into ASD etiology and treatment, the female side of animal models, such as prenatal valproic…
Preview only. Read the full abstract at the source