Progress in neuro-psychopharmacology & biological psychiatryHumansMaleAdolescentFemaleMajor Depressive Disorder
Structure-function coupling alterations in adolescent depression correlate with neurotransmitter systems and cell-type-specific transcriptomics.
Peiyi Wu, Ziyi Wang, Caijiu Deng, Yifang Zhou, Xiaowei Jiang, Lingtao Kong, Yuning Zhou, Qikun Sun, Ting Sun, Zhengjiao Tuo, Lei Wang, Yuang Liu, Yuxin Shen, Yanqing Tang
Published: 202510.1016/j.pnpbp.2025.111573
Abstract
BACKGROUND: Adolescent major depressive disorder (AMDD) emerges during a period of significant neurobiological reorganization, yet its specific pathophysiological mechanisms remain poorly understood. This study investigated structural-functional brai…
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