Progress in neuro-psychopharmacology & biological psychiatryAnimalsClozapineDizocilpine MaleateElectroencephalographyMale
Clozapine mitigates MK-801-induced mismatch negativity impairment in a rat electroencephalography study: relevance for schizophrenia drug development.
Florian W Adraoui, Maëlle Violas, Geoffrey Viardot, Kenza Hettak, Samuel Tugler, Eric Delpy, Anne Maurin, Philippe L'Hostis, Christophe Drieu La Rochelle, Kevin Carvalho
Published: 202510.1016/j.pnpbp.2025.111555
Abstract
Treating people with schizophrenia still represents a major challenge for neuropsychiatric drug development companies. While available atypical antipsychotics are mainly effective on positive symptoms of schizophrenia, their effects on cognitive and…
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