Progress in neuro-psychopharmacology & biological psychiatryAnimalsFemalePregnancySertralinePhysical Conditioning
The effect of sertraline and voluntary exercise during pregnancy on litter characteristics and postpartum affective behaviour in rat dams.
Noor S Jarbou, Olivia Mairinger, Elise Kulen, Lucas Mushahwar, Samara Walpole, Jasmine Matthews, Simon Maksour, Katrina Weston-Green, Mirella Dottori, Kelly A Newell
Published: 202510.1016/j.pnpbp.2025.111520
Abstract
INTRODUCTION: Sertraline is the frontline pharmacotherapy for the treatment of depression and anxiety during pregnancy. However, there is little evidence regarding the effects of sertraline on maternal behaviour or the maternal brain. Furthermore, th…
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