Progress in neuro-psychopharmacology & biological psychiatryAnimalsGuanfacineAttention Deficit Disorder with HyperactivityMaleAdrenergic alpha-2 Receptor Agonists
Oral guanfacine treatment ameliorates the ADHD-like symptoms caused by developmental manganese exposure.
Ellie Fisher, Stephane A Beaudin, Barbara J Strupp, Donald R Smith
Published: 202510.1016/j.pnpbp.2025.111517
Abstract
Epidemiological studies have linked developmental manganese (Mn) exposure to increased risk of ADHD and related symptoms in children and adolescents. Rodent model studies have 1) confirmed causality by demonstrating that developmental Mn exposure can…
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