Progress in neurobiology
The YAP/SCAP/SREBP1 pathway in astrocytes: A novel target for treating neonatal hypoxic-ischemic encephalopathy.
Jiaojiao Wang, Chunfang Dai, Hao Yuan, Qiuyun Tian, Qian Xiao, Xiaohuan Li, Xiuyu Shi, Zhifang Dong
Published: 202510.1016/j.pneurobio.2025.102869
Abstract
Astrocytes play a significant role in the pathogenesis of hypoxic-ischemic encephalopathy (HIE), contributing to neuroexcitotoxicity and inflammatory responses. However, the specific pathways through which astrocytes influence neurons remain incomple…
Preview only. Read the full abstract at the source