Placenta
Complement factor H-point mutation promotes the development of preeclampsia-like phenotype with multiparity in mice.
Fei-Fei Chen, Zheng Li, Ying Tan, Hui Wang, Shi Chen, Feng Yu, Ying-Dong He, Qian Chen, Hui-Xia Yang, Ming-Hui Zhao
Published: 202510.1016/j.placenta.2025.12.010
Abstract
INTRODUCTION: Preeclampsia, a severe pregnancy disorder associated with the placenta, remains incompletely understood in terms of its pathogenesis. Studies have suggested a link between complement activation and preeclampsia. In normal pregnancy, the…
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