Placenta
Determination of residue aspirin and its bioactive metabolites in human placenta: Application to high-risk to preeclampsia women received prophylactic low-dose aspirin.
Kenean Getaneh Tlaye, So Pui Kin, Gashaw Garedew Woldeamanuel, Bo Wah Leung, Liona C Poon, Chi Chiu Wang
Published: 202510.1016/j.placenta.2025.11.004
Abstract
INTRODUCTION: The human placenta plays central role in preeclampsia (PE) pathogenesis and may modulate the effectiveness of prophylactic low-dose aspirin (LDA). In this study, we optimized and validated LC-MS/MS method to quantify the residual acetyl…
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