Phytomedicine : international journal of phytotherapy and phytopharmacologyAnimalsSpinal Cord InjuriesAutophagyFlavanonesMicroglia
Naringenin alleviates spinal cord injury by ameliorating macrophage/microglia autophagy via progranulin stabilisation.
Chao Wang, Weihang Zhu, Ziran Wei, Zihan Cui, Yunqing Chen, Ronghan Liu, Tianrui Wang, Lu Zhang
Published: 202610.1016/j.phymed.2026.157785
Abstract
BACKGROUND: Autophagy plays a crucial role in the recovery of neural function after spinal cord injury (SCI) by modulating the inflammatory microenvironment. Naringenin (NGN) is a flavanone with anti-inflammatory activity; however, the effects and sp…
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