Phytomedicine : international journal of phytotherapy and phytopharmacologyTumor MicroenvironmentSTAT3 Transcription FactorHumansJanus Kinase 2Glucosides
Targeting the JAK2/STAT3 Axis and Remodeling the Tumour Microenvironment: The Dual Anti-Tumour Mechanism of Total Glucosides of Paeony in Gallbladder Cancer.
Kai-Nan Lin, Xue-Fei Yu, Zhi-Hao Lin, Yu-Kai Shan, Zhang-Guo Ying, He Feng, Li-Zhuo Zhang, Yan-Yang Liu, Hui-Ze Shen, Yang-Jian Hong, Qing-Lin Li, Ren-An Jin
Published: 202610.1016/j.phymed.2025.157756
Abstract
BACKGROUND: Gallbladder cancer (GBC) is the most prevalent malignancy of the biliary tract, emphasizing the urgent requirement for the development of effective drugs. Here, we present our findings on total glucosides of paeony (TGP), an active compou…
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