Phytomedicine : international journal of phytotherapy and phytopharmacologyHypoxia-Inducible Factor 1alpha SubunitEmodinTissue AdhesionsAnimals
Unveiling the active component of HuoXueTongFu formula: Emodin attenuates postoperative intra-abdominal adhesion by inhibiting HIF-1α-mediated glycolytic reprogramming.
Yanqi Chen, Jia Miao, Lili Yang, Yunda Fang, Yuheng Lian, Guanlu Li, Ziyang Kong, Linbo Zhang, Li Zeng, Yaoyao Bian
Published: 202610.1016/j.phymed.2025.157719
Abstract
BACKGROUND: Postoperative intra-abdominal adhesion (IA), driven by hypoxia, remains a global surgical challenge due to the lack of effective therapeutic interventions. Although the herbal HuoXueTongFu Formula (HXTF) has positive effects on adhesion f…
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