Phytomedicine : international journal of phytotherapy and phytopharmacologyAnimalsPPAR gammaArthritisRheumatoidMacrophages
Sanmiao pill ameliorates rheumatoid arthritis via PPARγ-mediated lipid accumulation in macrophage: A multi-omics and experimental validation.
Quanao Jiang, Xiaoman Jiang, Shi Lin Xia, Yanhong Bu, Yan Wang, Hong Wu, Ran Deng
Published: 202610.1016/j.phymed.2025.157697
Abstract
BACKGROUND: The enhanced infiltration of M1-polarized macrophages into synovium acts as a central driver of chronic inflammation characteristics of rheumatoid arthritis (RA). Sanmiao pill (SMP), a classic traditional formulation, has long been employ…
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