Phytomedicine : international journal of phytotherapy and phytopharmacologyAnimalsFlavanonesDietHigh-FatNon-alcoholic Fatty Liver Disease
Inhibiting VEGFC - mediated hepatocyte - macrophage regulatory axis contributes to protective effects of naringin against high - fat diet - induced hepatic fibrosis.
Jingya Li, Ao Nie, Xinyi Li, Zheng Chen, Kai Xu, Junbin Yan, Kannan Yao, Xiaojie Lin, Wei Mao, Zhiyun Chen, Wei Hong
Published: 202610.1016/j.phymed.2025.157682
Abstract
BACKGROUND: Naringin (NAR) has shown anti-fibrotic effects. This study found it alleviates non-alcoholic steatohepatitis (NASH)-associated liver fibrosis and downregulates vascular endothelial growth factor C (VEGFC). However, the pathophysiological…
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