Phytomedicine : international journal of phytotherapy and phytopharmacologyPhosphofructokinase-2Pancreatic NeoplasmsAnimalsHumansGlycolysis
Bruceine A abrogates pancreatic cancer metastasis by suppressing PFKFB4-glycolysis-EMT axis.
Si-Nan Lu, Meng-Yu Dai, Wei Liu, Di Di, Wei-Wei Tao, Jin-Ao Duan, Cai Lu, Ming Zhao
Published: 202610.1016/j.phymed.2025.157665
Abstract
BACKGROUND: Pancreatic cancer (PC), a highly aggressive malignancy of the digestive system, creates an urgent need for innovative antimetastatic strategies. Emerging evidence positions aerobic glycolysis as a critical metabolic driver of cancer disse…
Preview only. Read the full abstract at the source