Phytomedicine : international journal of phytotherapy and phytopharmacologyAnimalsVentricular RemodelingMyocardial InfarctionPyrazinesSirtuin 1
Tetramethylpyrazine alleviates ventricular remodeling after myocardial infarction by regulating Sirt1/p300/Yy1/sST2 signaling axis.
Ting Liu, Rui Zhang, Tianyu Wang, Zhirui Fang, Ying Guo, Yuming Fan, Xinze Li, Nawen Liu, Ping Liu, Shaoxia Wang, Lu Chen, Qi Liu, Hong Wang
Published: 202610.1016/j.phymed.2025.157662
Abstract
BACKGROUND: Adverse ventricular remodeling following myocardial infarction (MI) is a critical factor in the progression of heart failure (HF). However, clinical interventions are limited by the lack of reliable biomarkers and targeted therapies. Solu…
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