Phytomedicine : international journal of phytotherapy and phytopharmacologyAmaryllidaceae AlkaloidsAnimalsPhenanthridinesCarcinomaHepatocellular
Lycorine suppresses hepatocellular carcinoma via the reprogramming of myeloid and epithelial cells.
Xinyu Gu, Fuqiang Ma, Yafeng Liu, Shujun Zhang, Wenjuan Chen, Lifan Zhang, Lele Zhang, Juan Lu, Xinjun Hu
Published: 202610.1016/j.phymed.2025.157657
Abstract
BACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive malignancy associated with an immunosuppressive tumor microenvironment (TME), which contributes to resistance to therapy. Lycorine, a natural alkaloid, has demonstrated anticancer potential,…
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