Phytomedicine : international journal of phytotherapy and phytopharmacologyAnimalsTriterpenesCognitive DysfunctionGastrointestinal MicrobiomeReishi
Ganoderma lucidum triterpenes ameliorate age-related cognitive impairment via regulating Eubacterium lentum-mediated serine metabolism.
Zhihao Zhou, Tengjie Yu, Zhongbo Wang, Feng Xu, Wei Liu, Haoyu Ai, Tingting Zhang, Ke Ding, Qi Chen, Yiyue Yan, Hao Hao, Lin Su, Nan Jia, Xiayu Qian, Xin Fan
Published: 202510.1016/j.phymed.2025.157557
Abstract
BACKGROUND: Natural aging of the brain is commonly accompanied by a decline in cognitive ability, which is driven by oxidative stress, inflammation, and metabolic dysregulation. These pathological processes are further exacerbated by gut microbiota d…
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