Phytomedicine : international journal of phytotherapy and phytopharmacologyNon-alcoholic Fatty Liver DiseaseAnimalsMiceInbred C57BLLiver Cirrhosis
Moronic acid alleviates non-alcoholic fatty liver disease and fibrosis through PPARs-mediated lipidomic reprogramming.
Jinlu Han, Jiong Chen, Hong Hu, Yun Song, Mengyan Chen, De Zhao, Wen Shan, Qinghui Zhang, Ling Xu
Published: 202510.1016/j.phymed.2025.157519
Abstract
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) and its fibrotic progression represent major global health concerns with limited pharmacological interventions. Moronic acid (MA), a natural pentacyclic triterpenoid, has demonstrated anti-inflamm…
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