Phytomedicine : international journal of phytotherapy and phytopharmacologyAnimalsAnthraquinonesMiceMaleShock
Diacerein attenuates sepsis shock mortality through combined suppression of vascular inflammation, stiffness, and permeability.
Minghao Luo, Yi Jiang, Yuce Peng, Dingyi Lv, An He, Longxiang Huang, Yong Xia, Suxin Luo, Yuanjing Li
Published: 202510.1016/j.phymed.2025.157510
Abstract
BACKGROUND AND AIM: Sepsis shock mortality remains critically high due to dysregulated vascular inflammation and permeability. Diacerein (DIA), an anthraquinone derivative with anti-inflammatory properties, shows promise, but its vascular protective…
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