Phytomedicine : international journal of phytotherapy and phytopharmacologyNF-E2-Related Factor 2ColitisUlcerativeAnimalsHumans
Houttuynia cordata-derived nanoparticles stabilize mitochondrial dynamics to alleviate ulcerative colitis via the Nrf2/Ho-1 pathways.
Wenyi Zhuang, Mengqi Qu, Yang Guan, Jieli Pan, Yan Tai, Guanqun Xie, Xiaohui Chen, Feiye Zhu
Published: 202510.1016/j.phymed.2025.157505
Abstract
BACKGROUND: Ulcerative colitis (UC), a chronic inflammatory bowel disease, faces limited treatment efficacy and safety concerns. Extracellular vesicles (EVs) offer a promising nanoplatform for targeted therapy. PURPOSE: This study aimed to isolate an…
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