Phytomedicine : international journal of phytotherapy and phytopharmacologySTAT3 Transcription FactorFemaleHumansMesenchymal Stem CellsOvarian Neoplasms
Guizhi-Fuling Wan suppresses carcinoma-associated mesenchymal stem cells-induced ovarian cancer progression via STAT3 inhibition.
Mengwei Xue, Zixuan Bu, Kaile Ke, Jiawei Tian, Xingzheng Zheng, Nouri Neamati, Jianhui Ma, Haiyun Yu, Wei Li, Qing Dong, Fangfang Chen, Tiangong Lu
Published: 202510.1016/j.phymed.2025.157475
Abstract
BACKGROUND: Ovarian cancer (OC) is the most lethal gynecological malignancy. While carcinoma-associated mesenchymal stem cells (CA-MSCs) in tumor microenvironment are known to facilitate OC progression, the underlying mechanisms remain incompletely u…
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