Phytomedicine : international journal of phytotherapy and phytopharmacologyAnimalsSirtuin 3Signal TransductionLiver CirrhosisReceptors
Syringin attenuates fibrogenesis and inflammation through SIRT3-regulated P2X7 receptor signaling pathway in hepatic fibrosis.
Wan-Ling Wang, Xi-Yao Feng, Xin Guo, Hai-Ming Sun, Yu-Chen Jiang, Li-Qiang Shi, Jian Song
Published: 202510.1016/j.phymed.2025.157461
Abstract
BACKGROUND: Hepatic fibrosis manifests with impaired extracellular matrix (ECM) deposition and inflammation within the liver. This study probes deep into the hepatoprotective effects and underlying mechanisms of syringin (SY) against hepatic fibrosis…
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