Phytomedicine : international journal of phytotherapy and phytopharmacologyAnimalsLiver NeoplasmsHepatic Stellate CellsCell CommunicationMice
Hydroxylsafflower yellow A modulates tumor vascularization in liver cancer through intercellular communication and extracellular matrix-receptor interactions.
Xinyan Xue, Ke Fu, Mengling Zhou, Yanzhi Li, Shu Dai, Chuantao Zhang, Yao He, Xiaofang Xie, Yunxia Li
Published: 202510.1016/j.phymed.2025.157455
Abstract
BACKGROUND: Fibrosis represents a critical pathological feature in the progression of liver cancer, wherein the activation of hepatic stellate cells (HSCs) plays an important role. Hydroxylsafflower yellow A (HSYA), a chalcone C-glycoside compound, h…
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