Phytomedicine : international journal of phytotherapy and phytopharmacologyAnimalsThrombosisMicePolysaccharidesPlatelet Glycoprotein GPIIb-IIIa Complex
Tetrastigma hemsleyanum polysaccharides as natural inhibitors of platelet thrombosis via GPIIb/IIIa and MAPK pathways.
Kewei Li, Chenjun Shen, Peihao Xu, Leilei Zhu, Mingyuan Zhou, Baodong Ye, Yingzhi Shen, Zhishan Ding
Published: 202510.1016/j.phymed.2025.157439
Abstract
BACKGROUND: Thrombosis, driven by abnormal platelet activation and fibrin clot formation, is a key pathological basis of cardiovascular disorders. Polysaccharide-based agents, such as heparin, possess distinct antithrombotic activities. Tetrastigma h…
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