Phytomedicine : international journal of phytotherapy and phytopharmacologyAnimalsArtemisiaOxidative StressFerroptosisChemical and Drug Induced Liver Injury
Artemisia keiskeana Miq. alleviates oxidative stress and ferroptosis in APAP-induced liver injury by mediating Nrf2/GPX4/NF-κB signaling pathway through ESR1.
Yu Zhang, Qinwei Lu, Yiting Yan, Junhao Zhang, Tao Liu, Li Yu, Qianqian Fan, Kaifeng Wei
Published: 202510.1016/j.phymed.2025.157436
Abstract
BACKGROUND: Acetaminophen (APAP) can induce liver injury and even acute liver failure (ALF) or death when administered in overdose. Current treatments may be associated with significant adverse effects, so it is urgent to explore other safe and effec…
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