Phytomedicine : international journal of phytotherapy and phytopharmacologyQuinolizinesColitisUlcerativeHumansAnimals
Oxymatrine ameliorates ulcerative colitis via improving epithelial barrier function through targeting DSG2.
Pengyan Li, Xin Jin, Yi Li, Yunjiao Shen, Jiangpeng Wu, Ning Kang, Xinchi Feng, Feng Qiu
Published: 202510.1016/j.phymed.2025.157370
Abstract
BACKGROUND: Oxymatrine (OMT), an alkaloid isolated from Sophora flavescens Ait., is effective in treating ulcerative colitis (UC). However, its molecular mechanism of action remains unclear. PURPOSE: This research aimed to assess the therapeutic effe…
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