Phytomedicine : international journal of phytotherapy and phytopharmacologyGastrointestinal MicrobiomeAnimalsDrugsChinese HerbalColorectal Neoplasms
Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by attenuating the malignancy of cancer stem cells via the gut microbiota-bile acid-FXR axis.
Ye Zhang, Meng Shen, Jianaer Baokan, Liting Xu, Mingxin Ni, Junyan Jin, Weixing Shen, Dongdong Sun, Liu Li, Yueyang Lai, Qiuying Yan, Chengtao Yu, Jiani Tan, Changliang Xu, Lihuiping Tao
Published: 202510.1016/j.phymed.2025.157366
Abstract
BACKGROUND: Shen-Bai-Jie-Du decoction (SBJDD), a traditional Chinese herbal formula grounded in evidence-based medicine, demonstrates efficacy in reducing the recurrence and carcinogenesis of colorectal adenoma (CRA). However, the mechanism by which…
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