Pharmacological research
Purinosomes and mitochondria: Dynamic interactomes at the crossroads of metabolism, cell structure, and disease.
Andrea Mancini, Elisabetta Betterini, Matteo Bordi, Francesco Cecconi
Published: 202610.1016/j.phrs.2026.108096
Abstract
Mitochondria are central hubs of cellular metabolism, integrating nutrient catabolism, ATP production, redox balance, and biosynthetic precursor supply. Recent work has revealed that their influence extends beyond canonical bioenergetics to include i…
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