Pharmacological researchHumansAnimalsNeoplasmsSolute Carrier ProteinsCarcinogenesis
SLC transporters as metalloptotic gatekeepers in tumorigenesis: From molecular mechanisms to clinical potential.
Bingchen Pan, Tan Li, Na Deng, Xin Zhang, Yangjie Peng, Yanke Li, Jingjing Jing, Liping Sun
Published: 202510.1016/j.phrs.2025.108061
Abstract
Solute carrier (SLC) transporters exert a crucial effect on metalloptosis in tumors via governing the translocation of ions and amino acids across cellular and organelle membranes. Disruptions in metal ion homeostasis mediated by SLC transporters, al…
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