Protein expression and purificationChromatographyAffinityAntibodiesBispecificAnimals
The superiority of MabSelect VL, Cytiva's second-generation Protein L resin, over three other affinity resins in purifying a VHH-containing trispecific antibody.
Ruomei Lv, Wenjing Qi, Yifeng Li
Published: 202610.1016/j.pep.2025.106873
Abstract
Affinity chromatography is widely utilized for initial product capture in antibody purification. Besides Protein A resins, other affinity resins that bind different subdomains of an antibody have also been developed. For example, Protein L resin, Kap…
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