Photodiagnosis and photodynamic therapy
Photoactivated quercetin as an inhibitor of Porphyromonas gingivalis virulence factor Kgp and biofilms: Validation through in vitro assays, molecular docking, and ADMET profiling.
Maryam Pourhajibagher, Mohammadreza Moeininejad, Bahman Rahimi Esboei, Ehsan Kazemi Moghaddam, Abbas Bahador
Published: 202510.1016/j.pdpdt.2025.105272
Abstract
BACKGROUND: Porphyromonas gingivalis is a key pathogen in periodontitis, significantly contributing to biofilm formation and immune system evasion through virulence factors such as lysine-specific gingipain (Kgp). Kgp, a protease produced by P. gingi…
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